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Panel 2 (Male Diagnostic Panel)

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Description

Panel 2 (Male Diagnostic Panel)

Panel 2 (Male Diagnostic Panel)

An extended male-focused diagnostic profile covering autoimmune markers, digestive enzymes, cancer risk indicators, immunoglobulins, hormones, and metabolic health.

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What to Expect During Your Panel 2 Health Check

Your Panel 2 (Male Diagnostic Panel) is a detailed blood test that offers insight into your hormone levels, digestive enzymes, immune system, prostate health, cancer risk, metabolic function, and more. Here’s what to expect at every stage of your appointment:

🕒 Before Your Appointment

Fasting: You may be advised to fast for 8–10 hours before your test to ensure accuracy for certain components (e.g., C-peptide, lipase, leptin).

Hydration: Drink plenty of water the day before and the morning of your test.

Medications: Continue regular medications unless advised otherwise.

Timing: Morning appointments are preferred for hormone-related tests (e.g., leptin, testosterone if added).

🧪 During Your Appointment (Approx. 15–20 mins)

A trained phlebotomist will collect a blood sample from your arm.

You may be asked about your symptoms or medical history to support interpretation.

No physical examination is required.t

📬 After Your Appointment

Your sample is sent to a UK-accredited laboratory for analysis.

Results are typically available within 3–5 working days.

You’ll receive an easy-to-understand digital results report with:

Green/Amber/Red flag indicators

Detailed explanation of each result

Follow-up advice or GP referral guidance

🩺 Optional Add-ons

You may combine this test with:

Thyroid function panel

Testosterone and hormone profile

Cardiac screening

Digestive or allergy testing

What’s Included & What Each Test Means

Serum Folate (Vitamin B9)

  • Purpose: Essential for red blood cell production, DNA synthesis, and neurological function
  • Low levels may indicate: Nutritional deficiency, malabsorption, anaemia, or alcohol abuse
  • Why it matters: Folate deficiency can cause fatigue, mood changes, and increase homocysteine levels (a cardiovascular risk)

Vitamin B12

  • Purpose: Vital for nerve function, brain health, and red blood cell formation
  • Low B12 may cause: Fatigue, brain fog, tingling in hands/feet, or megaloblastic anaemia
  • Monitored in: Vegans, vegetarians, older adults, and patients with digestive disorders

C-Peptide

  • Purpose: Assesses natural insulin production by the pancreas
  • Why it matters: Helps differentiate between type 1 and type 2 diabetes or insulin resistance
  • Useful in: Diabetes diagnosis, insulinoma investigation, and monitoring hypoglycaemia

Parathyroid Hormone (PTH)

  • Purpose: Regulates calcium and phosphate levels in the blood
  • High levels may suggest: Parathyroid dysfunction or vitamin D deficiency
  • Linked to: Bone density issues, kidney disease, or unexplained high calcium levels

Creatinine Kinase (CK)

  • Purpose: A muscle enzyme released when muscle damage occurs
  • Elevated in: Muscle injury, inflammation (myositis), heart attacks, or after intense exercise
  • Assesses: Muscle health, statin side effects, and unexplained muscle pain

Rheumatoid Factor (RF)

  • Purpose: Autoantibody test for Rheumatoid Arthritis
  • May also rise in: Lupus, Sjögren’s, or chronic infections
  • Important when: Investigating joint pain, stiffness, or autoimmune disorders

Amylase & 8. Lipase

  • Purpose: Digestive enzymes to assess pancreatic function
  • Raised in: Pancreatitis, pancreatic injury, gallstones, or alcohol-related disease
  • Symptoms suggesting this test: Abdominal pain, nausea, upper GI symptoms

Prostate Profile PR2

  • Includes: Prostate-Specific Antigen (PSA) and possibly Free PSA ratio
  • Purpose: Screens for prostate inflammation, enlargement, or cancer risk

Recommended for: Men over 45, especially with urinary symptoms or family history

CA 19-9 (Cancer Antigen 19-9)

  • Purpose: Tumour marker for pancreatic, gastrointestinal, and bile duct cancers
  • May also rise in: Inflammation or benign GI conditions
  • Not diagnostic alone, but useful for monitoring or supporting clinical suspicion

CEA (Carcinoembryonic Antigen)

  • Purpose: Tumour marker linked to bowel (colorectal), lung, pancreatic, or breast cancers
  • Also elevated in: Smoking or inflammation
  • Used in: Cancer monitoring and recurrence detection

Immunoglobulin Panel (IgA, IgG, IgM)

  • Purpose: Evaluates immune system status
  • Abnormal levels suggest: Immune deficiency, chronic infection, or autoimmune disease

Low IgA: Seen in coeliac disease; affects test interpretation for some antibodies

Total IgE (Immunoglobulin E)

  • Purpose: Detects allergic predisposition and overactive immune responses
  • Elevated in: Asthma, eczema, allergies, parasitic infection
  • Why it matters: Useful in unexplained rashes, sinusitis, or recurrent respiratory symptoms

Tissue Transglutaminase IgA (tTG-IgA)

  • Purpose: Primary screening test for Coeliac Disease
  • Positive in: Autoimmune response to gluten, with intestinal inflammation

Note: Only valid if IgA levels are normal (hence the inclusion of total IgA)

Leptin

  • Purpose: A hormone regulating appetite and fat storage
  • Low levels: May contribute to overeating, weight gain, and metabolic dysfunction
  • High levels: Seen in obesity or leptin resistance
  • Useful in: Weight loss resistance, metabolic syndrome, and hormonal imbalance

Frequently Asked Questions

What is Panel 2 for?

Panel 2 is a comprehensive male-focused diagnostic panel that evaluates multiple aspects of your health, including:

  • Vitamin & hormone status
  • Immune function
  • Prostate and cancer markers
  • Pancreatic health
  • Autoimmune activity
  • Appetite/metabolic hormone (Leptin)

It’s ideal for men with unexplained symptoms such as fatigue, weight gain, digestive issues, inflammation, or those seeking full health reassurance.

Do I need to fast for this test?

Yes, fasting for 8–10 hours is recommended—especially for accurate C-peptide, leptin, and lipid-related readings. Water is encouraged.

Can this test detect cancer?

This panel includes tumour markers (CA19-9 and CEA) and a prostate-specific test (PR2), which may raise suspicion of underlying cancer, but cannot diagnose cancer on their own. They are best used for screening and monitoring when interpreted alongside symptoms, imaging, and specialist review.

What if my test shows something abnormal?
  • You’ll receive clear explanation and referral guidance within your report.
  • Any critical or urgent results will be flagged for immediate contact and action.
  • You may be advised to see your GP, urologist, endocrinologist, or gastroenterologist, depending on the result.
Why is leptin tested?

Leptin is a hormone involved in regulating hunger and fat storage. Abnormal levels may point to:

  • Obesity or leptin resistance
  • Fatigue and metabolic slowdown
  • Hormonal dysregulation, especially in men with weight concerns or suspected insulin resistance
Can I add other tests to this panel?

Absolutely. You can customise your panel by adding:

  • Testosterone & hormone profile
  • Cardiovascular risk markers (Lipoprotein (a), hs-CRP)
  • Gut microbiome or digestive health panel
  • Advanced men’s wellness MOT
How will I get my results?
  • Results are available through your private online dashboard, with a downloadable PDF.
  • You’ll receive an email or text notification as soon as they’re ready.
  • The report includes full interpretations and next-step guidance.
What’s included in the 24/7 GP helpline?

You’ll get 12 months of unlimited access to a private GP helpline for advice on general health issues, minor ailments, travel advice, and prescriptions. Please note: this service is not for discussing your health check results—those should be reviewed with your own GP.

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