£250.00
£250.00
This advanced hormone panel provides a comprehensive analysis of the female reproductive hormonal axis, assessing ovarian function, pituitary regulation, and androgen status. It is essential for investigating the causes of:
This panel evaluates the hypothalamic-pituitary-ovarian (HPO) axis, providing an integrated snapshot of hormonal balance and regulatory feedback.
Physiological role: Primary oestrogen in premenopausal women, secreted by developing ovarian follicles. Supports endometrial proliferation and prepares the uterus for implantation.
Clinical relevance: High E2: May reflect follicular cysts, early pregnancy, or oestrogen-secreting tumours. Low E2: Suggests diminished ovarian reserve, menopause, hypothalamic amenorrhoea, or premature ovarian insufficiency (POI). Essential for evaluating menopausal transition, HRT monitoring, or IVF cycles.Produced by: Anterior pituitary
Function: Stimulates follicular development in the ovary. Diagnostic interpretation: High FSH (>10–15 IU/L early cycle): Indicates poor ovarian reserve, perimenopause or menopause. Low FSH: Seen in hypogonadotropic hypogonadism, functional hypothalamic amenorrhoea (e.g. stress, low BMI, excessive exercise). FSH is most accurately measured on day 2–5 of the cycle for ovarian reserve testing.Secreted by: Corpus luteum after ovulation Function: Prepares the endometrium for implantation; supports early pregnancy Timing: Best measured 7 days post-ovulation (e.g., Day 21 in a 28-day cycle) Interpretation: >30 nmol/L: Indicates successful ovulation <10 nmol/L: Suggests anovulation or luteal phase insufficiency, which may impair fertility Also useful in monitoring progesterone support during IVF/luteal phase.
Source: Anterior pituitary Function: Stimulates lactation; inhibits ovulation by suppressing GnRH Elevated prolactin may cause: Amenorrhoea Galactorrhoea Infertility Hypogonadism Consider pituitary microadenoma if prolactin >1000 mIU/L Stress, sleep, and physical stimulation can temporarily raise prolactin – ideally measured in a calm, fasting state.
Produced by: Ovaries & adrenal glands Function: Supports libido, mood, metabolic balance, and bone health Elevated levels: Common in PCOS, congenital adrenal hyperplasia (CAH), adrenal tumours, or androgen-secreting ovarian neoplasms Low levels: Associated with fatigue, low libido, or mood changes Combined with SHBG and FAI for clinical androgen index
Function: Binds circulating oestradiol and testosterone, regulating bioavailability High SHBG: Reduces free testosterone; often increased with oestrogen therapy, pregnancy, or hyperthyroidism Low SHBG: Linked to insulin resistance, PCOS, obesity, and androgen excess SHBG helps distinguish true androgen excess from transient elevations
Formula: (Total Testosterone / SHBG) × 100 Purpose: Estimates the biologically active testosterone in circulation High FAI: Suggests hyperandrogenism, frequently used in PCOS diagnosis Normal FAI: May help exclude clinically significant androgen excess when total testosterone is borderline
Yes, when FSH is persistently >30 IU/L and oestradiol is low, it strongly suggests menopause. Combined with symptoms (e.g. hot flashes, no periods >12 months), this supports diagnosis.
Yes. It assesses androgens (testosterone, FAI) and menstrual hormones. In PCOS, we often see:
Absolutely. It provides key baseline data on ovulation, ovarian reserve, luteal function, and endocrine balance — all crucial for IVF, ovulation induction, or IUI protocols.
Yes, ideally. Hormonal contraception and HRT suppress natural hormone production, which may distort results. Speak with your clinician about stopping medication at least 4–6 weeks before testing, if safe to do so.
This profile is designed for women, but Testosterone, SHBG, FAI, and Prolactin are also relevant for men — especially when investigating low libido, erectile dysfunction, or fatigue. A Male Hormone Panel is more appropriate for male patients.
