£295.00
£295.00
In-depth Autoimmune & Inflammatory Marker Assessment
Rheumatologic diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), gout, and connective tissue disorders are often complex, multisystemic, and progressive. Early and accurate detection of immune dysfunction and inflammatory activity is crucial for initiating timely treatment, preserving joint function, and preventing organ involvement.
This comprehensive diagnostic panel investigates the immunological, inflammatory, and haematological markers commonly involved in systemic autoimmune disease. It helps clinicians:
This foundational test evaluates:
White cell count (WBC) – Inflammation or immune suppression
Red blood cells and haemoglobin – Anaemia of chronic disease, common in SLE or RA
Platelets – Often raised in active inflammation or low in immune-related cytopenias
Changes in FBC can reflect chronic inflammation, bone marrow suppression, or systemic autoimmune involvement.
An autoantibody directed against the Fc portion of IgG.
Present in 70–80% of RA patients May also be found in SLE, Sjögren’s syndrome, hepatitis C, and in some healthy individuals (especially the elderly) High titres are associated with more aggressive disease and extra-articular manifestationsA non-specific but sensitive indicator of systemic inflammation.
Often elevated in RA, vasculitis, temporal arteritis, and lupus Especially useful when interpreted alongside CRP to distinguish between acute and chronic inflammatory processesA liver-produced acute-phase protein that rises in response to tissue injury or inflammation.
Correlates more strongly with acute flares or infection CRP is often normal in lupus, but typically elevated in RA, vasculitis, and polymyalgia rheumatica Useful for monitoring disease activity or response to treatmentA highly specific marker for rheumatoid arthritis:
Often positive years before symptoms develop Strongly associated with erosive disease and poor prognosis Negative RF and positive CCP is still diagnostic of RA Combined with RF, this test increases diagnostic sensitivity and specificity significantly.Measures the level of urate in the blood:
Elevated levels are associated with gout, particularly if >360 µmol/L Urate crystals can deposit in joints, leading to acute inflammation and pain Also useful in assessing renal function and cardiovascular risk, which are comorbid in many autoimmune conditionsReferral to a rheumatologist Imaging studies (e.g., joint ultrasound, MRI) Additional antibody testing (e.g., ANA, ENA, dsDNA, complement levels)
This panel provides strong laboratory support for diagnosing conditions like RA and lupus but must be interpreted alongside clinical examination and imaging. A diagnosis is typically made by a rheumatologist using a combination of history, physical findings, labs, and sometimes imaging.
Yes. Markers like CRP, ESR, and FBC are useful for monitoring disease activity, flares, and response to immunosuppressive therapy (e.g., methotrexate, biologics).
While RF is classically associated with RA, it may also be elevated in:
Yes, possibly. Depending on the findings, we may suggest:
Yes. Especially in people with:
Generally, no. But let your clinician know if you're taking:
