Description
Coeliac Blood Test
🌾 Service Overview
This advanced coeliac screening panel is designed to detect immune responses triggered by gluten ingestion—essential for diagnosing coeliac disease, a chronic autoimmune condition where gluten damages the small intestine. The test identifies key antibodies that signal an immune-mediated reaction and intestinal damage, even in early or mild cases.
✅ What’s Included?
Tissue Transglutaminase IgA (tTG-IgA)
A highly sensitive marker for intestinal inflammation and mucosal damage caused by gluten.
Total Serum IgA
Checks for IgA deficiency, which can affect test accuracy. Low IgA levels are more common in people with coeliac disease.
Deamidated Gliadin Peptide (DGP-IgG)
Ideal for those with low IgA or in early coeliac presentation. Detects immune reactivity to gliadin (a component of gluten).
Endomysial Antibodies (EMA-IgA)
A highly specific confirmatory antibody test. A positive result strongly supports the diagnosis of coeliac disease.
Clinical Review & Follow-up Guidance
Personalised interpretation of your results with expert advice on: Whether further testing (e.g., biopsy) is recommended How to manage a potential gluten sensitivity or coeliac diagnosis Lifestyle and nutritional guidance
🔄 Optional Add-ons (available at additional cost):
Vitamin and Mineral Panel – Common deficiencies in coeliac include B12, iron, folate, and vitamin D
Bone Health Assessment – Evaluates osteoporosis risk due to nutrient malabsorption
Genetic Testing – HLA-DQ2/DQ8 typing to assess genetic predisposition to coeliac disease
🧑⚕️ Who Should Consider This Test?
This test is ideal if you:
Experience unexplained digestive issues, bloating, fatigue, or nutrient deficiencies
Have a family history of coeliac disease
Are considering starting a gluten-free diet and want clarity beforehand
Have autoimmune conditions (e.g., Type 1 diabetes, thyroid disease), which increase coeliac risk
đź“‹ Important Note:
To ensure accuracy, continue eating gluten regularly for at least 6 weeks prior to testing unless otherwise advised by a clinician.
Frequently Asked Questions
Coeliac disease is a serious autoimmune condition where your immune system reacts to gluten (a protein found in wheat, rye, and barley), causing damage to the lining of your small intestine. This can lead to digestive problems, nutrient deficiencies, and long-term health complications if left untreated.
Symptoms vary widely and may include:
- Bloating, diarrhoea, or constipation
- Fatigue or tiredness
- Unexplained weight loss
- Anaemia (low iron)
- Skin rash (dermatitis herpetiformis)
- Bone or joint pain
- Infertility
- Delayed growth in children
Some people may have no obvious symptoms but still experience internal damage.
Yes. For accurate results, you must be consuming gluten regularly (e.g., in bread, pasta, or cereals) for at least 6 weeks prior to testing. If you've already started a gluten-free diet, please speak to our clinical team for advice.
This test is primarily designed for adults, but children can also be tested. We recommend contacting us first if you're considering this test for a child under 16, so we can guide you appropriately.
This blood test is a powerful screening tool that looks for antibodies associated with coeliac disease. However, a positive result does not confirm the diagnosis alone. Further testing, such as an intestinal biopsy via referral to a gastroenterologist, may be required.
A negative result doesn't always rule out coeliac disease. If you're experiencing ongoing symptoms, you may need additional investigations for other conditions like non-coeliac gluten sensitivity, IBS, or inflammatory bowel disease (IBD).
Your results will be delivered securely via our online wellness dashboard and app, with a downloadable PDF report. You'll also receive clinical review and follow-up guidance tailored to your results.
You will receive personalised follow-up advice, including whether you should:
- See your GP for further tests
- Be referred to a specialist
- Consider dietary changes or additional nutrient testing
Our team is here to support you every step of the way.
Yes. Many of our clients choose to combine this test with:
- Vitamin & mineral panel (to check for deficiencies caused by coeliac disease)
- Bone health assessment (to detect osteoporosis risk)
- Digestive health panel or comprehensive health MOTs




